Welcome to CLC bio: Revolutionizing Genomics and Bioinformatics

Since its founding on January 4th, 2005, by brothers Bjarne and Thomas Knudsen, CLC bio has been on a mission to transform the field of genomics and bioinformatics. What began as a vision to create user-friendly software for molecular biology has grown into a global leader in Next Generation Sequencing (NGS) data analysis, celebrated for its innovative algorithms and cutting-edge solutions.

Our Journey: A Legacy of Innovation

Early Days

CLC bio’s journey started with the launch of CLC Sequence Viewer, a free program that quickly became a favorite among researchers for its ease of use and functionality. By the end of 2005, the company introduced its first commercial product, marking the beginning of a rapidly expanding portfolio.

Despite initial challenges—like rebranding from "Geniematics" after a naming conflict and creating a surplus of unused software boxes—CLC bio persevered with a strong global mindset, achieving over 1 million downloads by 2008.

The Turning Point

In 2007, a strategic pivot toward Next Generation Sequencing (NGS) data analysis set the stage for unprecedented growth. This focus led to the development of advanced solutions for high-throughput sequencing data, solidifying CLC bio’s market position and earning accolades such as the Best of Show Award at the Bio-IT World Conference and Expo in 2009.

 

Game-Changing Technology and Milestones

De Novo Assembler

CLC bio’s de novo assembly algorithm is redefining benchmarks in the industry. Highlights include:

  • 38-fold coverage of the human genome in just 7 hours on a single computer.

  • Significant improvements in data quality and processing efficiency.

Public beta trials are set to roll out soon, allowing researchers worldwide to test this revolutionary tool.

Bioinformatics Cube

The Bioinformatics Cube was an ambitious venture into FPGA technology. While advancements in SIMD technology shifted priorities, the Cube remains a symbol of innovation, sparking conversations at conferences and exhibitions.


 
Award-Winning Solutions for NGSWith solutions like CLC Genomics Server, CLC bio empowers researchers to analyze high-throughput sequencing data across all major NGS platforms. These tools simplify complex workflows, enabling scientists to focus on discovery and innovation.

 
Highlights from Our PublicationsNew Benchmarks in De Novo AssemblyCLC bio’s internal Alpha testing of its de novo assembler has yielded groundbreaking results, setting a new standard for speed and quality in genome assembly. A public beta trial is coming soon—sign up now to be part of the revolution.PacBio’s 3rd Gen Sequencing SpecsAs part of our commitment to staying ahead of technological trends, we track the latest developments, like PacBio’s single-molecule real-time DNA sequencer. With reduced costs and faster run times, this technology is shaping the future of genomics.The $1,000 GenomeIllumina’s innovative sequencing technology is pushing the boundaries of affordability and accessibility, offering DNA decoding at unprecedented speeds and costs. CLC bio remains at the forefront, integrating these advancements into its solutions.

At CLC bio, innovation isn't confined to software development and bioinformatics tools; it extends into creative explorations that showcase the dynamic and forward-thinking culture of the company. One such project was the auditory representation of the word "BIOINFORMATICS." This unique experiment transformed a term synonymous with data and algorithms into an engaging and imaginative soundscape, highlighting the team's playful yet deeply creative spirit. By giving "BIOINFORMATICS" a literal sound, CLC bio bridged the gap between science and art, reminding everyone that even in the highly technical world of genomics, there’s room for creativity and fun. This project not only demonstrates the team's ingenuity but also serves as a testament to CLC bio's belief in thinking outside the box and finding inspiration in unexpected places. Through initiatives like this, CLC bio continues to cultivate a work environment where innovation flourishes, ideas flow freely, and the boundaries of possibility are constantly expanded.